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1

Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

Sauna, Zuben E., Shukla, Suneet, Ambudkar, Suresh V.

Journal:

Molecular BioSystems

Year:

2005

Language:

english

File:

PDF, 469 KB

english, 2005

2

Curcuminoids purified from turmeric powder modulate the function of human multidrug resistance protein 1 (ABCC1)

Wanida Chearwae, Chung-Pu Wu, H. -Y. Chu, T. Randall Lee, Suresh V. Ambudkar, Pornngarm Limtrakul

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 460 KB

english, 2006

3

Synonymous Mutations and Ribosome Stalling Can Lead to Altered Folding Pathways and Distinct Minima

Chung-Jung Tsai, Zuben E. Sauna, Chava Kimchi-Sarfaty, Suresh V. Ambudkar, Michael M. Gottesman, Ruth Nussinov

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 597 KB

english, 2008

4

BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER1

Ambudkar, Suresh V., Dey, Saibal, Hrycyna, Christine A., Ramachandra, Muralidhara, Pastan, Ira, Gottesman, Michael M.

Journal:

Annual Review of Pharmacology

Year:

1999

Language:

english

File:

PDF, 467 KB

english, 1999

5

Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells

Songyot Anuchapreeda, Pranee Leechanachai, Melissa M Smith, Suresh V Ambudkar, Porn-ngarm Limtrakul

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 324 KB

english, 2002

6

Disulfiram is a potent modulator of multidrug transporter Cdr1p of Candida albicans

Suneet Shukla, Zuben E. Sauna, Rajendra Prasad, Suresh V. Ambudkar

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 824 KB

english, 2004

7

Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein

Zeidel, Mark L., Ambudkar, Suresh V., Smith, Barbara L., Agre, Peter

Journal:

Year:

1992

Language:

english

File:

PDF, 825 KB

english, 1992

8

Botryllamides: Natural Product Inhibitors of ABCG2

Henrich, Curtis J., Robey, Robert W., Takada, Kentaro, Bokesch, Heidi R., Bates, Susan E., Shukla, Suneet, Ambudkar, Suresh V., McMahon, James B., Gustafson, Kirk R.

Journal:

ACS Chemical Biology

Year:

2009

Language:

english

File:

PDF, 1.27 MB

english, 2009

9

Relationship Between Drugs and Functional Activity of Various Mammalian P-Glycoproteins (ABCB1)

Ambudkar, Suresh, Kim, In-Wha, Booth-Genthe, Catherine

Journal:

Mini Reviews in Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 165 KB

english, 2008

10

Tuning store-operated calcium entry to modulate Ca2+-dependent physiological processes

Ong, Hwei Ling, Subedi, Krishna Prasad, Son, Ga-Yeon, Liu, Xibao, Ambudkar, Indu Suresh

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2018

Language:

english

File:

PDF, 2.40 MB

english, 2018

11

The Endoplasmic Reticulum–Plasma Membrane Junction: A Hub for Agonist Regulation of Ca 2+ Entry

Ong, Hwei Ling, Ambudkar, Indu Suresh

Journal:

Cold Spring Harbor Perspectives in Biology

Year:

2019

Language:

english

File:

PDF, 1.06 MB

english, 2019

12

ChemInform Abstract: Synthesis and Analysis of Polyethylene Glycol Linked P-Glycoprotein-Specific Homodimers Based on (-)-Stipiamide.

Merritt B. Andrus, Timothy M. Turner, Emily P. Updegraff, Zuben E. Sauna, Suresh V. Ambudkar

Journal:

Year:

2001

File:

PDF, 29 KB

2001

13

Synthesis and analysis of polyethylene glycol linked P-glycoprotein-specific homodimers based on (−)-stipiamide

Merritt B Andrus, Timothy M Turner, Emily P Updegraff, Zuben E Sauna, Suresh V Ambudkar

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 77 KB

english, 2001

14

Synthesis and preliminary analysis of a P-glycoprotein-specific [3H]-benzophenone photoaffinity label based on (−)-stipiamide

Merritt B Andrus, Timothy M Turner, Zuben E Sauna, Suresh V Ambudkar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 155 KB

english, 2000

15

Plasma membrane calcium ATPase (PMCA4): A housekeeper for RT-PCR relative quantification of polytopic membrane proteins

Anna Maria Calcagno, Katherine J Chewning, Chung-Pu Wu, Suresh V Ambudkar

Journal:

BMC Molecular Biology

Year:

2006

Language:

english

File:

PDF, 426 KB

english, 2006

16

Effects of phosphorylation of P-glycoprotein on multidrug resistance

Ursula A. Germann, Timothy C. Chambers, Suresh V. Ambudkar, Ira Pastan, Michael M. Gottesman

Journal:

Journal of Bioenergetics and Biomembranes

Year:

1995

Language:

english

File:

PDF, 850 KB

english, 1995

17

Purification and reconstitution of functional human P-glycoprotein

Suresh V. Ambudkar

Journal:

Journal of Bioenergetics and Biomembranes

Year:

1995

Language:

english

File:

PDF, 637 KB

english, 1995

18

Heterologous expression systems for P-glycoprotein:E. coli, yeast, and baculovirus

Gregory L. Evans, Baofu Ni, Christine A. Hrycyna, David Chen, Suresh V. Ambudkar, Ira Pastan, Ursula A. Germann, Michael M. Gottesman

Journal:

Journal of Bioenergetics and Biomembranes

Year:

1995

Language:

english

File:

PDF, 919 KB

english, 1995

19

Differential effects of the immunosuppressive agents cyclosporin A, tacrolimus and sirolimus on drug transport by multidrug resistance proteins

Attaphol Pawarode, Suneet Shukla, Hans Minderman, Stacy M. Fricke, Elaine M. Pinder, Kieran L. O’Loughlin, Suresh V. Ambudkar, Maria R. Baer

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2007

Language:

english

File:

PDF, 428 KB

english, 2007

20

Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells

Robert W. Robey, Tomasz Obrzut, Suneet Shukla, Orsolya Polgar, Sira Macalou, Julian C. Bahr, Attilio Di Pietro, Suresh V. Ambudkar, Susan E. Bates

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 530 KB

english, 2009

21

Genomics and the mechanism of P-glycoprotein (ABCB1)

Zuben E. Sauna, In-Wha Kim, Suresh V. Ambudkar

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2007

Language:

english

File:

PDF, 180 KB

english, 2007

22

Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin

Pornngarm Limtrakul, Wanida Chearwae, Suneet Shukla, Chada Phisalphong, Suresh V. Ambudkar

Journal:

Molecular and Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 343 KB

english, 2007

23

Curcumin Inhibits the Activity of ABCG2/BCRP1, a Multidrug Resistance-Linked ABC Drug Transporter in Mice

Suneet Shukla, Hani Zaher, Anika Hartz, Björn Bauer, Joseph A. Ware, Suresh V. Ambudkar

Journal:

Pharmaceutical Research

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

24

Sipholenol A, a marine-derived sipholane triterpene, potently reverses P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells

Zhi Shi, Sandeep Jain, In-Wha Kim, Xing-Xiang Peng, Ioana Abraham, Diaa T.A. Youssef, Li-Wu Fu, Khalid El Sayed, Suresh V. Ambudkar, Zhe-Sheng Chen

Journal:

Year:

2007

Language:

english

File:

PDF, 291 KB

english, 2007

25

Association of the ABCG2 C421A polymorphism with prostate cancer risk and survival

Erin R. Gardner, Christoph M. Ahlers, Suneet Shukla, Tristan M. Sissung, Sandra B. Ockers, Douglas K. Price, Akinobu Hamada, Robert W. Robey, Seth M. Steinberg, Suresh V. Ambudkar, William L. Dahut, W

Journal:

BJU International

Year:

2008

Language:

english

File:

PDF, 199 KB

english, 2008

26

Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5)

Chung-Pu Wu, Anna Maria Calcagno, Stephen B. Hladky, Suresh V. Ambudkar, Margery A. Barrand

Journal:

Year:

2005

Language:

english

File:

PDF, 396 KB

english, 2005

27

NCX1 Surface Expression : A Tool to Identify Structural Elements of Functional Importance

HANNAH RAHAMIMOFF, XIAOYAN REN, CHAVA KIMCHI-SARFATY, SURESH AMBUDKAR, JUDITH KASIR

Journal:

Annals of the New York Academy of Sciences

Year:

2002

File:

PDF, 5.29 MB

2002

28

Structure of a multidrug transporter

Gottesman, Michael M, Ambudkar, Suresh V, Xia, Di

Journal:

Nature Biotechnology

Year:

2009

Language:

english

File:

PDF, 647 KB

english, 2009

29

P-glycoprotein: from genomics to mechanism

Ambudkar, Suresh V, Kimchi-Sarfaty, Chava, Sauna, Zuben E, Gottesman, Michael M

Journal:

Year:

2003

Language:

english

File:

PDF, 474 KB

english, 2003

30

Overview: ABC Transporters and Human Disease

Michael M. Gottesman, Suresh V. Ambudkar

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2001

Language:

english

File:

PDF, 57 KB

english, 2001

31

Preface

Michael M. Gottesman, Suresh V. Ambudkar

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2001

Language:

english

File:

PDF, 8 KB

english, 2001

32

The Mechanism of Action of Multidrug-Resistance-Linked P-Glycoprotein

Zuben E. Sauna, Melissa M. Smith, Marianna Müller, Kathleen M. Kerr, Suresh V. Ambudkar

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2001

Language:

english

File:

PDF, 372 KB

english, 2001

33

Synthesis and Characterization of a BODIPY Conjugate of the BCR-ABL Kinase Inhibitor Tasigna (Nilotinib): Evidence for Transport of Tasigna and Its Fluorescent Derivative by ABC Drug Transporters

Shukla, Suneet, Skoumbourdis, Amanda P., Walsh, Martin J., Hartz, Anika M. S., Fung, King Leung, Wu, Chung-Pu, Gottesman, Michael M., Bauer, Björn, Thomas, Craig J., Ambudkar, Suresh V.

Journal:

Molecular Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 4.33 MB

english, 2011

34

Saracatinib (AZD0530) is a potent modulator of ABCB1-mediated multidrug resistance in vitro and in vivo

Ke-Jun Liu, Jie-Hua He, Xiao-Dong Su, Hong-May Sim, Jing-Dun Xie, Xing-Gui Chen, Fang Wang, Yong-Ju Liang, Satyakam Singh, Kamlesh Sodani, Tanaji T. Talele, Suresh V. Ambudkar, Zhe-Sheng Chen, Hai-Yin

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 631 KB

english, 2012

35

Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes

Chung-Pu Wu, Antonios Klokouzas, Stephen B. Hladky, Suresh V. Ambudkar, Margery A. Barrand

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 257 KB

english, 2005

36

Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1®

Robert W. Robey, Suneet Shukla, Elizabeth M. Finley, Robert K. Oldham, Daryl Barnett, Suresh V. Ambudkar, Tito Fojo, Susan E. Bates

Journal:

Biochemical Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.14 MB

english, 2008

37

Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478

Zhi Shi, Amit K. Tiwari, Suneet Shukla, Robert W. Robey, In-Wha Kim, Smitaben Parmar, Susan E. Bates, Qiu-Sheng Si, Curtis S. Goldblatt, Ioana Abraham, Li-Wu Fu, Suresh V. Ambudkar, Zhe-Sheng Chen

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

38

Sensitization of ABCB1 overexpressing cells to chemotherapeutic agents by FG020326 via binding to ABCB1 and inhibiting its function

Chun-ling Dai, Yong-ju Liang, Li-ming Chen, Xu Zhang, Wen-jing Deng, Xiao-dong Su, Zhi Shi, Chung-pu Wu, Charles R. Ashby Jr., Shin-ichi Akiyama, Suresh V. Ambudkar, Zhe-sheng Chen, Li-wu Fu

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 443 KB

english, 2009

39

Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells

Ioana Abraham, Sandeep Jain, Chung-Pu Wu, Mohammad A. Khanfar, Yehong Kuang, Chun-Ling Dai, Zhi Shi, Xiang Chen, Liwu Fu, Suresh V. Ambudkar, Khalid El Sayed, Zhe-Sheng Chen

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 552 KB

english, 2010

40

In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs

Hong-May Sim, Chung-Pu Wu, Suresh V. Ambudkar, Mei-Lin Go

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 520 KB

english, 2011

41

The power of the pump: Mechanisms of action of P-glycoprotein (ABCB1)

Suresh V. Ambudkar, In-Wha Kim, Zuben E. Sauna

Journal:

European Journal of Pharmaceutical Sciences

Year:

2006

Language:

english

File:

PDF, 372 KB

english, 2006

42

Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance

Pornsiri Pitchakarn, Shinobu Ohnuma, Komsak Pintha, Wilart Pompimon, Suresh V. Ambudkar, Pornngarm Limtrakul

Journal:

The Journal of Nutritional Biochemistry

Year:

2012

Language:

english

File:

PDF, 929 KB

english, 2012

43

Functional reconstitution of prokaryote and eukaryote membrane proteins

Peter C. Maloney, Suresh V. Ambudkar

Journal:

Archives of Biochemistry and Biophysics

Year:

1989

Language:

english

File:

PDF, 922 KB

english, 1989

44

Reconstitution of phosphate-linked antiport from Streptococcus,lactis

Suresh V. Ambudkar, Peter C. Maloney

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 429 KB

english, 1985

45

The amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transport

Nidhi Puri, Manisha Gaur, Monika Sharma, Suneet Shukla, Suresh V. Ambudkar, Rajendra Prasad

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2009

Language:

english

File:

PDF, 1.23 MB

english, 2009

46

Divergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and noninterchangeable

Antresh Kumar, Suneet Shukla, Ajeet Mandal, Sudhanshu Shukla, Suresh V. Ambudkar, Rajendra Prasad

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2010

Language:

english

File:

PDF, 1.97 MB

english, 2010

47

The yeast Pdr5p multidrug transporter: How does it recognize so many substrates?

John Golin, Suresh V. Ambudkar, Leopold May

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 204 KB

english, 2007

48

Tyrosine kinase inhibitors as modulators of ABC transporter-mediated drug resistance

Suneet Shukla, Zhe-Sheng Chen, Suresh V. Ambudkar

Journal:

Drug Resistance Updates

Year:

2012

Language:

english

File:

PDF, 762 KB

english, 2012

49

The A-loop, a novel conserved aromatic acid subdomain upstream of the Walker A motif in ABC transporters, is critical for ATP binding

Suresh V. Ambudkar, In-Wha Kim, Di Xia, Zuben E. Sauna

Journal:

Year:

2006

Language:

english

File:

PDF, 363 KB

english, 2006

50

A novel way to spread drug resistance in tumor cells: functional intercellular transfer of P-glycoprotein (ABCB1)

Suresh V. Ambudkar, Zuben E. Sauna, Michael M. Gottesman, Gergely Szakacs

Journal:

Trends in Pharmacological Sciences

Year:

2005

Language:

english

File:

PDF, 1.36 MB

english, 2005

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